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Table 4 Data collection elements

From: Acute respiratory distress syndrome subphenotypes and therapy responsive traits among preclinical models: protocol for a systematic review and meta-analysis

Categories Main items
Study characteristics DOI, Num ID (specific number ID for the purpose of the meta-analysis), title, author, year, country and journal of publication, country of study, mono/multicentric
Study population (experimental model) Animal species or ex vivo model, age, gender, strain, weight, and comorbidity
Type of acute lung injury model As defined in Table 1, with timing
Intervention Type (see Table 2), number, timing, mode of administration, dose
Co-intervention Resuscitation fluids, antibiotics, mechanical ventilation parameters, mode of anesthesia, drugs, etc.
Preclinical endpoints As defined in Table 3
Risk of bias assessments (Cochrane risk of bias tool) Randomization, allocation, blinding and completeness of follow-up
Quality of reporting of individual preclinical studies ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines elements
  1. DOI digital object identifier