Skip to main content

Table 4 Data collection elements

From: Acute respiratory distress syndrome subphenotypes and therapy responsive traits among preclinical models: protocol for a systematic review and meta-analysis

Categories

Main items

Study characteristics

DOI, Num ID (specific number ID for the purpose of the meta-analysis), title, author, year, country and journal of publication, country of study, mono/multicentric

Study population (experimental model)

Animal species or ex vivo model, age, gender, strain, weight, and comorbidity

Type of acute lung injury model

As defined in Table 1, with timing

Intervention

Type (see Table 2), number, timing, mode of administration, dose

Co-intervention

Resuscitation fluids, antibiotics, mechanical ventilation parameters, mode of anesthesia, drugs, etc.

Preclinical endpoints

As defined in Table 3

Risk of bias assessments (Cochrane risk of bias tool)

Randomization, allocation, blinding and completeness of follow-up

Quality of reporting of individual preclinical studies

ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines elements

  1. DOI digital object identifier