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Table 4 Results of the Cox regression of time to first hospitalisation stratified in ILD-related and non-ILD-related

From: Hospitalisation patterns of patients with interstitial lung disease in the light of comorbidities and medical treatment – a German claims data analysis

  Non-ILD relatedILD-related
Hazard ratioP-valueHazard ratioP-value
SexMaleReference Reference 
Female0.970.02150.86<.0001
Age (in years) 1.01<.00011.02<.0001
EntitySARCReference Reference 
IIP1.18<.00011.43<.0001
OFI1.25<.00011.37<.0001
DAI1.47<.00011.170.1034
PNE1.070.05561.070.2349
RAP1.57<.00011.390.0002
EPP1.28<.00011.160.0073
HSP1.150.00111.060.3537
CTD1.91<.00011.020.7829
OSASIf present or occuring before event0.91<.00010.960.0165
DepressionIf present or occuring before event0.95<.00010.970.0259
DiabetesIf present or occuring before event0.96<.00010.93<.0001
GERDIf present or occuring before event0.96<.00011.000.9959
COPDIf present or occuring before event0.980.11471.35<.0001
CHDIf present or occuring before event1.17<.00011.19<.0001
Lung cancerIf present or occuring before event0.79<.00010.950.0068
Pulmonary hypertensionIf present or occuring before event0.970.00420.76<.0001
Number of comorbidities 1.18<.00011.11<.0001
Immunosuppressive drugsImmediate onsetReference Reference 
Late onset1.270.00021.42<.0001
Never0.980.56840.850.0002
Anti-fibrotic drugsImmediate onsetReference Reference 
Late onset0.920.47982.27<.0001
Never1.070.2261.030.7111
SteroidsImmediate onsetReference Reference 
Late onset1.24<.00011.64<.0001
Never0.91<.00010.71<.0001
  1. Significant estimates are printed in bold
  2. DAI Drug-Associated ILDs, CHD coronary heart disease, COPD chronic obstructive pulmonary disease, CTD Connective Tissue-associated ILD, EPP Eosinophilic Pneumonia, GERD Gastroesophageal Reflux Disease, HSP Hypersensitivity Pneumonitis, IIP Idiopathic Interstitial Pneumonia, ILD interstitial lung disease, OFI Other Fibrosing ILDs, PNE Pneumoconiosis, RAP Radiation-Associated Pneumonitis, SARC Sarcoidosis