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Table 4 Results of the Cox regression of time to first hospitalisation stratified in ILD-related and non-ILD-related

From: Hospitalisation patterns of patients with interstitial lung disease in the light of comorbidities and medical treatment – a German claims data analysis

  

Non-ILD related

ILD-related

Hazard ratio

P-value

Hazard ratio

P-value

Sex

Male

Reference

 

Reference

 

Female

0.97

0.0215

0.86

<.0001

Age (in years)

 

1.01

<.0001

1.02

<.0001

Entity

SARC

Reference

 

Reference

 

IIP

1.18

<.0001

1.43

<.0001

OFI

1.25

<.0001

1.37

<.0001

DAI

1.47

<.0001

1.17

0.1034

PNE

1.07

0.0556

1.07

0.2349

RAP

1.57

<.0001

1.39

0.0002

EPP

1.28

<.0001

1.16

0.0073

HSP

1.15

0.0011

1.06

0.3537

CTD

1.91

<.0001

1.02

0.7829

OSAS

If present or occuring before event

0.91

<.0001

0.96

0.0165

Depression

If present or occuring before event

0.95

<.0001

0.97

0.0259

Diabetes

If present or occuring before event

0.96

<.0001

0.93

<.0001

GERD

If present or occuring before event

0.96

<.0001

1.00

0.9959

COPD

If present or occuring before event

0.98

0.1147

1.35

<.0001

CHD

If present or occuring before event

1.17

<.0001

1.19

<.0001

Lung cancer

If present or occuring before event

0.79

<.0001

0.95

0.0068

Pulmonary hypertension

If present or occuring before event

0.97

0.0042

0.76

<.0001

Number of comorbidities

 

1.18

<.0001

1.11

<.0001

Immunosuppressive drugs

Immediate onset

Reference

 

Reference

 

Late onset

1.27

0.0002

1.42

<.0001

Never

0.98

0.5684

0.85

0.0002

Anti-fibrotic drugs

Immediate onset

Reference

 

Reference

 

Late onset

0.92

0.4798

2.27

<.0001

Never

1.07

0.226

1.03

0.7111

Steroids

Immediate onset

Reference

 

Reference

 

Late onset

1.24

<.0001

1.64

<.0001

Never

0.91

<.0001

0.71

<.0001

  1. Significant estimates are printed in bold
  2. DAI Drug-Associated ILDs, CHD coronary heart disease, COPD chronic obstructive pulmonary disease, CTD Connective Tissue-associated ILD, EPP Eosinophilic Pneumonia, GERD Gastroesophageal Reflux Disease, HSP Hypersensitivity Pneumonitis, IIP Idiopathic Interstitial Pneumonia, ILD interstitial lung disease, OFI Other Fibrosing ILDs, PNE Pneumoconiosis, RAP Radiation-Associated Pneumonitis, SARC Sarcoidosis