Fig. 1From: Lung volume dependence of respiratory function in rodent models of diabetes mellitusSchemes summarizing the pretreatment strategies (a) and the experimental protocol (b). Forced oscillation measurements and blood gas analyzes were performed at three different positive end-expiratory pressures (0, 3, and 6 cmH2O: PEEP0, PEEP3, and PEEP6, respectively). Forced oscillation respiratory mechanics were assessed at a PEEP of 3 cmH2O during provocation tests with increasing doses (2–32 μg/kg/min) of methacholine (MCh) following the baseline measurement (BL). Abbreviations: DM1, model of type 1 diabetes; DM2, model of type 2 diabetes; C, control group; STZ, streptozotocin in mg/kg; FRC, measurement of functional residual capacity; PREP, animal preparationsBack to article page