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Fig. 4 | Respiratory Research

Fig. 4

From: SOD2 ameliorates pulmonary hypertension in a murine model of sleep apnea via suppressing expression of NLRP3 in CD11b+ cells

Fig. 4

Flow cytometry analysis of percentage of CD11b+ cells in WT and SOD2−/+ mice. a-d. Representative view of flow cytometry graph of CD11b + cells in the blood of WT and SOD2−/+ mice. e. Percentage of CD11b+ cells in the peripheral blood mononuclear cells of the four groups analyzed by Flowjo software. f. Percentage of Ly6C+Ly6G cells and Ly6CLy6G+ cells in CD11b+ cells in the blood. g. Percentage of CD11b+ cells in the pulmonary mononuclear cells of the four groups. h. Percentage of Ly6C+Ly6G cells and Ly6CLy6G+ cells in CD11b+ cells in the lung. i. Percentage of CD11b+ cells in the bone marrow mononuclear cells of the four groups. j. Percentage of Ly6C+Ly6G cells and Ly6CLy6G+ cells in CD11b+ cells in the bone marrow. CON: Wild type mice in the normal air condition. CIH: Chronic intermittent hypoxia. WT: wild type mice. SOD2−/+: knock-down of SOD2 gene heterozygous mice. N = 5. Comparisons between multiple groups were performed using ANOVA with the Bonferroni test. *p < 0.05, **p < 0.01, ***p < 0.001

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