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Fig. 1 | Respiratory Research

Fig. 1

From: SOD2 ameliorates pulmonary hypertension in a murine model of sleep apnea via suppressing expression of NLRP3 in CD11b+ cells

Fig. 1

Expression of SOD2 in the plasma. a. Concentration of SOD2 in the plasma of both healthy donators (control) and OSA patients (mild, moderate, severe OSA). b. Relative mRNA expression of SOD2 in the control and chronic intermittent hypoxia (CIH) mice. c. Representative graph of western blot expression of SOD2 compared to β-actin. d. Ratio of SOD2/β-actin in the group of wild type (WT) mice and SOD2 knockdown mice under control or CIH condition. CON: Wild type mice in the normal air condition. CIH: Chronic intermittent hypoxia. WT: wild type mice. SOD2−/+: knock-down of SOD2 gene heterozygous mice. N = 5 in experiment of b and c. Comparisons between two groups were performed using unpaired T-test after normality distribution test. Comparisons between multiple groups were performed using ANOVA with the Bonferroni test.*p < 0.05, **p < 0.01, ***p < 0.001

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