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Fig. 4 | Respiratory Research

Fig. 4

From: Porcine versus bovine surfactant therapy for RDS in preterm neonates: pragmatic meta-analysis and review of physiopathological plausibility of the effects on extra-pulmonary outcomes

Fig. 4

Comparisons poractant-α vs bovine surfactants for IVH (a-b), NEC(c) and ROP (d). a and b illustrate meta-analyses of any dose of poractant-α vs bovine surfactants for IVH of any grade (1703 neonates) and for grade III-IV IVH (1672 neonates), respectively. c and d illustrate NEC and ROP of any stage (1097 and 962 neonates, respectively). Poractant-α and bovine surfactants are considered as treatment (Trt) and control (Ctrl) arm, respectively; events (Ev) per arm and odds ratio (95%CI) are reported. Squares and horizontal lines represent odds ratios and their 95%CI, respectively. The location of the diamond and its width represent the pooled estimated effect size and its 95%CI, respectively. All analyses have been performed with random-effects model

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