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Fig. 1 | Respiratory Research

Fig. 1

From: Exchange protein directly activated by cAMP (Epac) protects against airway inflammation and airway remodeling in asthmatic mice

Fig. 1

Expression of Epac1 and Epac2 in lung tissues of acute and chronic asthmatic mice. In acute asthma group, female BALB/c mice were sensitized at days 0 and 14 and challenged at days 25–27. Relative expression of Epac1 and Epac2 in lung tissues of acute asthmatic mice was measured by qPCR (a) and Western blot (b). In chronic asthma group, female BALB/c mice were sensitized at days 0, 7 and 14 and challenged 3 times a week after day 21 for 6 weeks. Relative expression of Epac1 and Epac2 in lung tissues of chronic asthmatic mice was measured by qPCR (c) and Western blot (d). Actin was used as a loading control. *Control vs Asthma. All data are expressed as mean ± SEM of three independent experiments (n = 4–6). ***P < 0.001; **P < 0.01; *P < 0.05

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