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Fig. 1 | Respiratory Research

Fig. 1

From: Comparative analyses of long non-coding RNA profiles in vivo in cystic fibrosis lung airway and parenchyma tissues

Fig. 1

Analyses of LncRNA in CF lung tissues. The expressions of LncRNA and corresponding mRNAs significantly (p < 0.05) altered in CF lung tissues compared to matched non-CF control tissues (n = 4 each) were analyzed by LncRNA arrays: a airway and b parenchyma tissues. Density plots depict the variation in expression: X and Y axes represent averaged normalized values in each group (log2). Volcano plots depict the fold-changes: each dot represents a single LncRNA or mRNA and is colored black unless it was differentially expressed. Hierarchical clustering and the heat map indicate the expression level of the transcripts significantly altered in CF tissues compared to non-CF controls: red represents increased expression, while green represents reduced expression. (CF-A, CF lung airway tissue; HBE-A, control airway tissue; CF-P, CF lung parenchyma tissue; HBE-P, control lung parenchyma)

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Respiratory Research

ISSN: 1465-993X

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