Table 1 Detailed information of the new asthma-targeted drugs
DrugBank ID | Name | Gene | Drug Groups | Formula | Disease | Gene Linked lncRNA |
|---|---|---|---|---|---|---|
DB00675 | Tamoxifen | PRKCE | approved | C26H29NO | Breast cancer | MIR17HG MALAT1 MAGI2-AS3 DAPK1-IT1 |
DB08877 | Ruxolitinib | JAK2 | approved | C17H18N6 | Essential thrombocythemia | MIR17HG MALAT1 MAGI2-AS3 DAPK1-IT1 |
DB00755 | Tretinoin | GPRC5A | approved; investigational; nutraceutical | C20H28O2 | Leukemia | MIR17HG MALAT1 MAGI2-AS3 DAPK1-IT1 |
DB04216 | Quercetin | STK17B | experimental; investigational | C15H10O7 | Obesity | MIR17HG MALAT1 MAGI2-AS3 |
DB01254 | Dasatinib | KIT | approved; investigational | C22H26ClN7O2S | Mast cell leukemia | MIR17HG MALAT1 MAGI2-AS3 CASC2 |
DB00583 | Levocarnitine | CPT1A | approved; investigational | C7H15NO3 | Nutritional deficiency | MIR17HG MALAT1 DAPK1-IT1 |
DB04552 | Niflumic Acid | PLA2G4A | experimental | C13H9F3N2O2 | Rheumatoid arthritis; Dysmenorrhea | MIR17HG MALAT1 MAGI2-AS3 |
DB01016 | Glyburide | KCNJ8 | approved | C23H28ClN3O5S | Type 2 diabetes | MIR17HG MALAT1 MAGI2-AS3 |