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Table 2 Incidence of Postoperative Pulmonary Complications (PPCs) by DLco Status

From: Impact of diffusing lung capacity before and after neoadjuvant concurrent chemoradiation on postoperative pulmonary complications among patients with stage IIIA/N2 non-small-cell lung cancer

 

PPC

Type of the PPC

Mortality

ARDS/Pneumonia

Respiratory failure

Air leakage

BPF/empyema

Atelectasis

30-day

90-day

Overall

79 (24.6)

49 (15.3)

23 (7.2)

19 (5.9)

14 (4.4)

10 (3.1)

2 (0.6)

26 (8.1)

DLco at diagnosis

 Normal (N = 165)

24 (14.5)

14 (8.5)

4 (2.4)

5 (3.0)

4 (2.4)

4 (2.4)

0 (0)

5 (3.0)

 Low (N = 156)

55 (35.3)

35 (22.4)

19 (12.2)

14 (9.0)

10 (6.4)

6 (3.9)

2 (1.3)

21 (13.5)

P value

<.001

.001

<.001

.024

.081

.533a

.234a

.001

Change before and after CCRT

 NN: Normal → Normal (N = 76)

7 (9.2)

3 (4.0)

0 (0)

1 (1.3)

2 (2.6)

1 (1.3)

0 (0)

1 (1.3)

 NL: Normal → Low (N = 89)

17 (19.1)

11 (12.4)

4 (4.5)

4 (4.5)

2 (2.3)

3 (3.4)

0 (0)

4 (4.5)

 LL: Low → Low (N = 75)

23 (31.7)

14 (18.7)

7 (9.3)

7 (9.3)

5 (6.7)

2 (2.7)

1 (1.3)

10 (13.3)

 LVL: Low → Very Low (N = 81)

32 (39.5)

21 (25.9)

12 (14.8)

7 (8.6)

5 (6.2)

4 (4.9)

1 (1.2)

11 (13.6)

P for trends

<.001

<.001

<.001

.030

.148

.255

.260

.002

  1. ARDS acute respiratory distress syndrome; BPF bronchopleural fistula; DLco diffusing capacity of the lung for carbon monoxide; PPC postoperative pulmonary complication;
  2. a Fisher’s exact test