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Table 1 Characteristics of Study Populations by PPC Development (N = 321)

From: Impact of diffusing lung capacity before and after neoadjuvant concurrent chemoradiation on postoperative pulmonary complications among patients with stage IIIA/N2 non-small-cell lung cancer

 

Overall (N = 321)

Development of PPC

No (N = 242)

Yes (N = 79)

P Value

Age (years)

61.1 (8.0)

60.4 (8.0)

63.3 (8.0)

.006

Sex

   

.017

 Male

289 (80.7)

188 (77.7)

71 (89.9)

 

 Female

62 (19.3)

54 (22.3)

8 (10.1)

 

BMI (kg/m2)

23.7 (3.1)

23.8 (3.1)

23.6 (3.1)

.670

Smoking status

   

.014

 Never

63 (19.6)

55 (22.7)

8 (10.1)

 

 Past or current

259 (80.4)

187 (77.3)

71 (89.9)

 

Histology

   

.120

 Adenocarcinoma

168 (52.3)

134 (55.4)

34 (43.0)

 

 Squamous cell

128 (39.8)

90 (37.2)

38 (48.1)

 

 Large cell

9 (2.8)

8 (3.3)

1 (1.3)

 

 Others

16 (5.0)

10 (4.1)

6 (7.6)

 

Type of surgery

   

.010

 Lobectomy

256 (79.8)

201 (83.1)

55 (69.6)

 

 Bilobectomy/Pneumonectomy

65 (20.2)

41 (16.9)

24 (30.4)

 

PFT before CCRT

 FVC, % of the predicted value

91.7 (15.1)

92.7 (14.8)

88.6 (15.8)

.036

 FEV1, % of the predicted value

82.8 (16.6)

84.4 (16.5)

77.8 (15.9)

.002

 FEV1/FVC, %

70.2 (9.6)

70.9 (9.4)

68.1 (10.1)

.003

 DLco, % of the predicted value

82.0 (17.5)

84.7 (17.7)

73.7 (14.1)

<.001

PFT after CCRT

 FVC, % of the predicted value

90.3 (13.7)

91.8 (13)

85.6 (14.8)

<.001

 FEV1, % of the predicted value

84.4 (14.6)

85.9 (14.1)

79.8 (15.2)

.001

 FEV1/FVC, %

70.8 (9.0)

71.2 (8.7)

69.5 (9.8)

.143

 DLco, % of the predicted value

69.7 (15.1)

72 (14.9)

62.8 (13.6)

<.001

Hemoglobin

 Before CCRT

13.6 (1.4)

13.6 (1.4)

13.5 (1.6)

0.793

 After CCRT

11.9 (1.5)

11.9 (1.5)

11.9 (1.6)

0.725

  1. Values in table are mean (SD), number (%), or median (interquartile range)
  2. BMI body mass index; CCRT concurrent chemoradiotherapy; DLco diffusing capacity of the lung for carbon monoxide; FEV1 forced expiratory volume in one second; FVC forced vital capacity; PFT pulmonary function test; PPC postoperative pulmonary complications