Fig. 4
From: Targeted regulation of fibroblast state by CRISPR-mediated CEBPA expression
CEBPA expression is enhanced by a G9a inhibitor and partially mediates its anti-fibrotic effects. a) qRT-PCR analysis of CEBPA expression in CEBPA knock down lung fibroblasts and their control with or without BIX01294 for 48 h. b-d) Oil Red O staining and their quantification in IPF fibroblasts with or without BIX01294 in the adipogenic medium for 10 days. e-h) qRT-PCR analysis showing ACTA2, COL1A1, FN1 and CTGF transcript levels in CEBPA knock down lung fibroblasts and their control with or without BIX01294 for 48 h. Data are expressed as mean ± SD (*p < 0.05, ** p < 0.01, ***p < 0.001, **** p < 0.0001)