TY - JOUR AU - Chung, K. F. AU - Wenzel, S. E. AU - Brozek, J. L. AU - Bush, A. AU - Castro, M. AU - Sterk, P. J. PY - 2014 DA - 2014// TI - International ERS / ATS guidelines on definition , evaluation and treatment of severe asthma JO - Eur Respir J VL - 43 UR - https://doi.org/10.1183/09031936.00202013 DO - 10.1183/09031936.00202013 ID - Chung2014 ER - TY - JOUR AU - Shaw, D. E. AU - Sousa, A. R. AU - Fowler, S. J. AU - Fleming, L. J. AU - Roberts, G. AU - Corfield, J. PY - 2015 DA - 2015// TI - Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort JO - Eur Respir J VL - 46 UR - https://doi.org/10.1183/13993003.00779-2015 DO - 10.1183/13993003.00779-2015 ID - Shaw2015 ER - TY - JOUR AU - Zeiger, R. S. AU - Schatz, M. AU - Li, Q. AU - Chen, W. AU - Khatry, D. B. AU - Gossage, D. PY - 2014 DA - 2014// TI - High blood eosinophil count is a risk factor for future asthma exacerbations in adult persistent asthma JO - J Allergy Clin Immunol Pract VL - 2 UR - https://doi.org/10.1016/j.jaip.2014.06.005 DO - 10.1016/j.jaip.2014.06.005 ID - Zeiger2014 ER - TY - JOUR AU - Price, D. B. AU - Rigazio, A. AU - Campbell, J. D. AU - Bleecker, E. R. AU - Corrigan, C. J. AU - Thomas, M. PY - 2015 DA - 2015// TI - Blood eosinophil count and prospective annual asthma disease burden : a UK cohort study JO - Lancet Respir VL - 3 UR - https://doi.org/10.1016/S2213-2600(15)00367-7 DO - 10.1016/S2213-2600(15)00367-7 ID - Price2015 ER - TY - JOUR AU - Sitkauskiene, B. AU - Johansson, A. AU - Sergejeva, S. AU - Lundin, S. AU - Sjo, M. AU - Lo, J. PY - 2004 DA - 2004// TI - Regulation of bone marrow and airway CD34+ Eosinophils by Interleukin-5 JO - Am J Respir Cell Mol Biol VL - 30 UR - https://doi.org/10.1165/rcmb.2002-0311OC DO - 10.1165/rcmb.2002-0311OC ID - Sitkauskiene2004 ER - TY - JOUR AU - Rosenberg, H. F. AU - Phipps, S. AU - Foster, P. S. PY - 2007 DA - 2007// TI - Eosinophil trafficking in allergy and asthma JO - J Allergy Clin Immunol VL - 119 UR - https://doi.org/10.1016/j.jaci.2007.03.048 DO - 10.1016/j.jaci.2007.03.048 ID - Rosenberg2007 ER - TY - JOUR AU - Nair, P. AU - Wenzel, S. AU - Rabe, K. F. PY - 2017 DA - 2017// TI - Oral glucocorticoid–sparing effect of Benralizumab in severe asthma JO - N Engl J Med VL - 376 UR - https://doi.org/10.1056/NEJMoa1703501 DO - 10.1056/NEJMoa1703501 ID - Nair2017 ER - TY - JOUR AU - Ortega, H. G. AU - Liu, M. C. AU - Pavord, I. D. AU - Brusselle, G. G. AU - Fitzgerald, J. M. AU - Chetta, A. PY - 2014 DA - 2014// TI - Mepolizumab treatment in patients with severe Eosinophilic asthma JO - N Engl J Med VL - 371 UR - https://doi.org/10.1056/NEJMoa1403290 DO - 10.1056/NEJMoa1403290 ID - Ortega2014 ER - TY - JOUR AU - Bjermer, L. AU - Lemiere, C. AU - Maspero, J. AU - Weiss, S. AU - Zangrilli, J. AU - Germinaro, M. PY - 2016 DA - 2016// TI - Reslizumab for inadequately controlled asthma with elevated blood eosinophil levels JO - Chest VL - 150 UR - https://doi.org/10.1016/j.chest.2016.03.032 DO - 10.1016/j.chest.2016.03.032 ID - Bjermer2016 ER - TY - JOUR AU - Corren, J. AU - Weinstein, S. AU - Janka, L. AU - Zangrilli, J. AU - Garin, M. PY - 2016 DA - 2016// TI - Phase 3 study of Reslizumab in patients with poorly controlled asthma, effects across a broad range of eosinophil counts JO - Chest VL - 150 UR - https://doi.org/10.1016/j.chest.2016.03.018 DO - 10.1016/j.chest.2016.03.018 ID - Corren2016 ER - TY - JOUR AU - Castro, M. AU - Zangrilli, J. AU - Wechsler, M. E. AU - Bateman, E. D. AU - Brusselle, G. G. AU - Bardin, P. PY - 2015 DA - 2015// TI - Reslizumab for inadequately controlled asthma with elevated blood eosinophil counts: results from two multicentre, parallel, double-blind, randomised, placebo-controlled, phase 3 trials JO - Lancet Respir Med VL - 3 UR - https://doi.org/10.1016/S2213-2600(15)00042-9 DO - 10.1016/S2213-2600(15)00042-9 ID - Castro2015 ER - TY - JOUR AU - Murphy, K. AU - Jacobs, J. AU - Bjermer, L. AU - Fahrenholz, J. M. AU - Shalit, Y. PY - 2017 DA - 2017// TI - Long-term Safety and Efficacy of Reslizumab in Patients with Eosinophilic Asthma JO - J Allergy Clin Immunol Pract VL - 5 UR - https://doi.org/10.1016/j.jaip.2017.08.024 DO - 10.1016/j.jaip.2017.08.024 ID - Murphy2017 ER -