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Table 5 Regression analysis for the relationship between serum bilirubin levels and mortalitya

From: Serum bilirubin level is associated with exercise capacity and quality of life in chronic obstructive pulmonary disease

 

Whole group

GOLD I-II

GOLD III-IV

HR (95% CI)

P-value

HR (95% CI)

P-value

HR (95% CI)

P-value

Univariate

 Baseline bilirubin

1.31 (0.53–3.24)

0.563

0.74 (0.14–3.79)

0.715

1.50 (0.49–4.57)

0.473

 Clustered analysis

0.16 (0.02–1.10)

0.062

0.14 (0.01–2.60)

0.188

0.17 (0.01–2.27)

0.180

Multipleb

 Baseline bilirubin

1.60 (0.65–3.97)

0.311

1.23 (0.24–6.26)

0.805

1.36 (0.47–3.88)

0.569

 Clustered analysis

0.19 (0.03–1.19)

0.076

0.21 (0.01–4.42)

0.315

0.33 (0.03–3.86)

0.377

  1. a ‘baseline bilirubin’ is the results of regression analysis for clinical outcomes according to the baseline bilirubin levels. ‘Clustured analysis’ is the results of regression analysis for clinical outcomes and repeated measured serum bilirubin levels
  2. b Adjusted for age, sex, body mass index, smoking (current and former), and baseline forced expiratory volume in 1 s
  3. GOLD Global Initiative for Chronic Obstructive Lung Disease, HR hazard ratio, CI confidence interval