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Table 1 Baseline demographics

From: Relationship between diffusion capacity and small airway abnormality in COPDGene

 

GOLD spirometry grade

0 (n = 957)

1–2 (n = 584)

3–4 (n = 305)

Age, yr

63.5

68.3

68.9

Sex, n (% female)

512 (54%)

249 (42%)

130 (43%)

BMI (kg/m2)

28.9

27.9

27.5

Smoking pack-years

37.1

49.8

55.0

Current smokers, n (%)

344 (36%)

212 (36%)

61 (20%)

Exacerbations in prior year

0.11

0.32

0.71

FEV1, L

2.73

2.03

0.98

FEV1% predicted

98.4

73.3

36.4

FVC, L

3.49

3.39

2.43

FVC % predicted

96.1

91.7

67.2

FEV1/FVC

0.78

0.60

0.41

DLCO, % predicted

90.1%

74.2%

51.2%

DLCO, GLI z-score

−0.73

−1.91

−4.08

PRMfSAD

10.0%

21.0%

34.6%

PRMEmph

1.8%

6.5%

18.3%

  1. All values expressed as mean except categorical variables expressed as n (%)
  2. BMI body mass index, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, DLCO single breath carbon monoxide diffusing capacity of the lung, GLI Global Lung Function Initiative, PRM parametric response mapping, fSAD functional small airways disease, Emph emphysema