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Table 2 Characteristics of the long-term survivors with stage III and stage IV non-small cell lung cancers

From: Analysis of key clinical features for achieving complete remission in stage III and IV non-small cell lung cancer patients

Variables

Stage III (n = 37)

Stage IV (n = 51)

P value

Age

 Median (Range) – years

66.0 (41-79)

64.0 (36-89)

0.56

Age distribution

 < 75 – no. (%)

30 (81.1)

43 (84.3)

0.69

 ≥ 75 – no. (%)

7 (18.9)

8 (15.7)

 

Sex – no. (%)

 Male

29 (78.4)

30 (58.8)

0.06

 Female

8 (21.6)

21 (41.2)

 

Smoking status

 Current

16 (43.2)

19 (37.3)

0.25

 Former

13 (35.1)

13 (25.5)

 

 Never

8 (21.6)

19 (37.3)

 

 BMI

22.2 ± 3.2

22.2 ± 3.4

0.74

Histological characteristics of tumor – no. (%)

 Adenocarcinoma

20 (54.1)

41 (80.4)

< 0.05

 Large cell carcinoma

0

1 (2)

 

 Squamous cell carcinoma

9 (24.3)

3 (5.9)

 

 Not otherwise specified

6 (16.2)

2 (3.92)

 

 Other cell types

2 (5.41)

4 (7.84)

 

 EGFR mutation status

Positive/Negative/Unknown

4 / 9 / 24

13 / 13 / 25

0.19

ECOG performance status – no. (%)

 1

17 (46.0)

22 (43.1)

0.79

 0

20 (54.1)

29 (56.9)

 

 Primary tumor diameter (mm; mean ±SD)

36.3 ± 19.3

34.1 ± 15.3

0.91

N factor - no. (%)

 N3

10 (8.11)

15 (29.4)

0.26

 N2

22 (59.5)

19 (37.3)

 

 N1

2 (5.41)

4 (7.8)

 

 N0

3 (8.11)

13 (25.5)

 

M factor - no. (%)

 M1c

0

9 (17.6)

 

 M1b

0

14 (27.5)

 

 M1a

0

28 (54.9)

 

 Total metastatic number at initial diagnosis

0

5.51 ± 4.13

 
  1. BMI body mass index, EGFR epidermal growth factor receptor, ECOG Eastern Cooperative Oncology Group.
  2. All significant P values are expressed in boldface, and not significant P values are expressed in plainface