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Table 2 Associations between Sputum AcPGP and clinical features of COPD

From: The matrikine acetyl-proline-glycine-proline and clinical features of COPD: findings from SPIROMICS

 

Model 1

Model 2#

 

Beta

S.E.

P-value

Beta

S.E.

P-value

FEV1, percent predicted

−2.58

1.38

0.063

n/a

n/a

n/a

FEV1/FVC

−0.02

0.007

0.018

n/a

n/a

n/a

FEF25–75, percent predicted

−2.40

1.20

0.046

n/a

n/a

n/a

GOLD Stage

0.14

0.05

0.004

n/a

n/a

n/a

CAT

0.93

0.52

0.073

0.55

0.49

0.27

PRM-emph

1.72

0.70

0.015

1.26

0.63

0.040

PRM-fSAD

1.67

0.81

0.040

1.08

0.70

0.127

  1. Model 1 = Linear regression models included sputum AcPGP, age, sex, current smoking status. #Model 2 = Linear regression model was adjusted for FEV1 percent predicted in addition to previously listed covariates (model 2 was not used for spirometric based outcome variables)