Case | Pathogen by culture & Nanopore | Resistance phenotype by culture | Clinically relevant resistance genes [N of alignments] |
---|---|---|---|
Resistance identified | |||
Case 1 | Stenotrophomonas maltophilia | R: ticarcillin/clavulanic acid R: ceftazidime | blaTEM-4 [4] blaTEM-112 [1] blaTEM-157 [1] blaACT-5 [1] |
I: levofloxacin | oqxB [1] | ||
Tetracycline not tested | tetC [6] | ||
Case 2 | Staphylococcus aureus | R: methicillin | mecA [4] |
R: erythromycin, clindamycin | ermA [10] erm (33) [1] | ||
tet38 [11] ant(4′)-lb [9] tetC [3] blaTEM-4 [1] | |||
Case 3 | Staphylococcus aureus | I: tetracycline | tetK [1] tet38 [1] tetQ [1] |
Case 4 | Escherichia coli | R: tetracycline | tetX [1] |
R: Trimethoprim-sulfamethoxazole R: ciprofloxacin, levofloxacin | sul1 [363] dfrA [127] | ||
acrF [315]a parE [304]a mfd [277]a | |||
mphA [215] aadA5 [196] vgaC [110] blaACT-5 [7] blaACT-14 [3] mefA [1] mel [1] | |||
No resistance identified | |||
Case 5 | Staphylococcus aureus | S: all tested agents | none |
Case 6 | Staphylococcus aureus | S: all tested agents | tet38 [2] blaTEM4 [2] |
Case 7 | Pseudomonas aeruginosa | S: all tested agents | none |
Resistance not tested | |||
Case 8 | Streptococcus agalactiae | Not tested | tetM [60] isaC [55] sul1 [2] tetQ [2] mphA [1] aadA5 [1] |