Fig. 2From: Single-inhaler triple therapy in patients with chronic obstructive pulmonary disease: a systematic reviewAnnual rate of moderate and severe exacerbations. COPD chronic obstructive pulmonary disease, FULFIL Lung FUnction and quality of LiFe assessment in COPD with closed trIpLe therapy, ICS inhaled corticosteroids, IMPACT InforMing the PAthway of COPD Treatment, LABA long-acting β2 agonist, LAMA long-acting muscarinic antagonistBack to article page