| # Studies | # Comparisons | SMD (95% CI) | % Weight | I^2 | p* | p** |
---|---|---|---|---|---|---|---|
Disease | Â | Â | Â | Â | Â | Â | Â |
 Asthma | 3 | 41 | 0.79 (0.59, 0.10) | 63.93 | 72.80 | 0.00 | 0.59 |
 BPD | 1 | 4 | 3.74 (3.13, 4.36) | 7.07 | 85.50 | 0.00 | |
 ARDS | 2 | 14 | 0.72 (0.41, 1.04) | 26.78 | 77.00 | 0.00 | |
 PH | 1 | 2 | 2.42 (1.32, 3.52) | 2.21 | 0.00 | 0.97 | |
Animal model/species | Â | Â | Â | Â | Â | Â | Â |
 Mouse | 5 | 40 | 1.61 (1.40, 1.82) | 60.98 | 79.60 | 0.00 | 0.00 |
 Rat | 2 | 21 | 0.10 (-0.17, 0.36) | 39.02 | 54.90 | 0.00 | |
Strain | Â | Â | Â | Â | Â | Â | Â |
 C57/BL6 | 4 | 36 | 1.33 (1.11, 1.56) | 53.91 | 70.30 | 0.00 | 0.00 |
 FVB | 1 | 4 | 3.74 (3.13, 4.36) | 7.07 | 85.50 | 0.00 | |
 Wistar | 2 | 21 | 0.10 (-0.17, 0.36) | 39.02 | 54.90 | 0.00 | |
Gender | Â | Â | Â | Â | Â | Â | Â |
 Male | 5 | 55 | 0.77 (0.60, 0.95) | 90.71 | 73.50 | 0.00 | 0.01 |
 Mixed | 1 | 4 | 3.74 (3.13, 4.36) | 7.07 | 85.50 | 0.00 | |
 Not reported | 1 | 2 | 2.42 (1.32, 3.52) | 2.21 | 0.00 | 0.97 | |
Age | Â | Â | Â | Â | Â | Â | Â |
 Neonatal | 1 | 4 | 3.74 (3.13, 4.36) | 7.07 | 85.50 | 0.00 | 0.00 |
 Adult | 5 | 53 | 0.80 (0.70, 1.06) | 84.90 | 74.50 | 0.00 | |
 Not reported | 1 | 4 | 0.12 (-0.46, 0.70) | 8.03 | 0.00 | 0.45 | |
Intervention characteristics | Â | Â | Â | Â | Â | Â | Â |
Asthma | Â | Â | Â | Â | Â | Â | 0.18 |
 Ovalbumin | 2 | 21 | 0.10 (-0.17, 0.36) | 39.02 | 54.90 | 0.00 | |
 Aspergillus exposure | 1 | 19 | 1.89 (1.56, 2.21) | 24.91 | 41.60 | 0.03 | |
ARDS | Â | Â | Â | Â | Â | Â | |
 LPS | 2 | 14 | 0.73 (.41, 1.04) | 26.78 | 77.00 | 0.00 | |
BPD | Â | Â | Â | Â | Â | Â | |
 75% hyperoxia | 1 | 4 | 3.74 (3.13, 4.36) | 7.07 | 85.50 | 0.00 | |
PH | Â | Â | Â | Â | Â | Â | |
 Hypoxia | 1 | 2 | 2.42 (1.32, 3.52) | 2.21 | 0.00 | 0.97 | |
Source | Â | Â | Â | Â | Â | Â | Â |
 Bone marrow | 6 | 57 | 1.10 (0.93, 1.27) | 91.97 | 81.40 | 0.00 |  |
 Adipose tissue | 1 | 4 | 0.12 (-0.46, 0.70) | 8.03 | 0.00 | 0.45 | 0.14 |
Origin | Â | Â | Â | Â | Â | Â | Â |
 Allogenic | 7 | 61 | 1.02 (0.86, 1.18) | 100.00 | 80.90 | 0.00 | 0.00 |
Dose | Â | Â | Â | Â | Â | Â | Â |
 200ul | 2 | 24 | 1.46 (1.17, 1.74) | 32.95 | 63.20 | 0.00 | 0.00 |
 50ul | 4 | 27 | 0.74 (0.50, 0.97) | 48.30 | 86.30 | 0.00 | |
 30ul | 1 | 10 | 0.99 (1.17, 1.74) | 18.75 | 81.20 | 0.00 | |
Delivery | Â | Â | Â | Â | Â | Â | Â |
 Intravenous | 5 | 43 | 1.19 (1.00, 1.39) | 68.50 | 80.20 | 0.00 | 0.08 |
 Intratracheal | 2 | 18 | 0.64 (0.35, 0.93) | 31.50 | 81.70 | 0.00 | |
Timing of treatment | Â | Â | Â | Â | Â | Â | Â |
 <72hr | 5 | 37 | 0.42 (0.22, 0.62) | 68.01 | 70.80 | 0.00 | 0.00 |
 >72hr | 2 | 24 | 2.30 (2.01, 2.59) | 31.99 | 71.40 | 0.00 |