| Mean Age | Median Age |
---|
Estimate (yrs) | SE | 95% CI | Estimate (yrs) | SE | 95% CI |
---|
Arg16 | 25.91* | 1.31 | 23.35–28.49 | 28.30* | 4.14 | 20.19–36.41 |
Gly16 | 21.80 | 0.59 | 20.86–23.42 | 22.17 | 0.40 | 21.38–22.96 |
Overall | 22.71 | 0.62 | 21.49–23.93 | 22.48 | 0.39 | 21.72–23.24 |
- SE standard error, CI confidence interval, Arg16: patients who were homozygous or heterozygous for the β2-adrenergic receptor (ADRB2) resulting in at least one arginine substitution at amino acid 16 (n = 26); Gly16: patients who were homozygous for ADRB2 resulting in a glycine substitution at amino acid 16 (n = 147). *Significant difference in mean or median age at first use of NV between genotype groups, P < 0.05