Fig. 1

PINK1 expression is reduced in IPF AMs. a Representative Western blot and b protein levels of PINK1 relative to actin in total BAL cell lysates from IPF (n = 19) and control subjects (n = 12) (patients characteristics Additional file 2: Table S2). c Immune staining of PINK1 in alveolar macrophages/monocytes and PINK1 mean fluorescence/cellper patient (d) and group (e). f PINK1 and g Parkin relative mRNA expression in BALF cells from IPF (n = 42) and control (n = 14) subjects normalized to GAPDH (patients characteristics Additional file 2: Table S3). (Data represented as median with interquartile range, *p < 0.05, **p < 0.01, Mann-Whitney test)