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Fig. 6 | Respiratory Research

Fig. 6

From: Enhanced Bruton’s tyrosine kinase in B-cells and autoreactive IgA in patients with idiopathic pulmonary fibrosis

Fig. 6

Increased Bruton’s tyrosine kinase (BTK) expression levels in B cells of IPF patients. (a) Mean fluorescence intensity (MFI) of BTK in all circulating B-cells (CD19+) and (b) naïve B-cells (CD27IgD+), IgD+ memory B-cells (CD27+IgD+) and IgD memory B-cells (CD27+IgD) of HCs and IPF patients. (c) BTK expression (MFI) in pulmonary B-cells of control lungs and IPF lungs. Non-parametric two-tailed Mann-Whitney test was used. Data are expressed as mean and dots represent individual patient values. * P < 0.05 ** P < 0.01

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