| Adjusted mean | Adjusted difference in mean relative to tertile 3 |  |  |  | |
---|---|---|---|---|---|---|
Tertile 3 (highest)a | Tertile 2b | Tertile 1 (lowest)b | P trend | Continuous β (95% CI), per 10 HU increaseb | P | |
N | 98 | 98 | 97 | Â | Â | Â |
PMD, median (min-max) | 50.66 (47.80 to 58.88) | 44.90 (41.65 to 47.73) | 37.60 (10.33–41.55) |  |  |  |
FVC, L | 2.94 ± 0.12 | − 0.05 (− 0.23 to 0.14) | − 0.08 (− 0.28 to 0.13) | 0.462 | 0.07 (− 0.04 to 0.19) | 0.207 |
FVC, % predicted | 105.18 ± 3.57 | −3.7 (−9.24 to 1.85) | −6.82 (− 13.05 to −0.59) | 0.031 | 4.64 (1.18 to 8.10) | 0.009 |
FEV1, L | 1.88 ± 0.08 | − 0.09 (− 0.22 to 0.05) | − 0.14 (− 0.29 to 0.01) | 0.063 | 0.14 (0.06 to 0.23) | 0.001 |
FEV1, % predicted | 90.65 ± 3.59 | −5.47 (−11.10 to 0.15) | − 10.28 (− 16.60 to − 3.97) | 0.001 | 8.56 (5.12 to 12.00) | < 0.001 |
FEV1/FVC | 0.64 ± 0.02 | − 0.02 (− 0.04 to 0.01) | − 0.03 (− 0.06 to − 0.01) | 0.018 | 0.04 (0.02 to 0.05) | < 0.001 |
mMRC | 2.04 ± 0.20 | 0.1 (− 0.21 to 0.41) | 0.14 (− 0.21 to 0.49) | 0.431 | −0.17 (− 0.37 to − 0.02) | 0.077 |
CAT score | 21.80 ± 1.69 | 0.81 (−1.86 to 3.47) | 1.76 (−1.23 to 4.75) | 0.247 | −1.82 (−3.48 to −0.16) | 0.032 |
Emphysema index | 4.14 ± 1.17 | 2.05 (0.22 to 3.88) | 2.80 (0.73 to 4.86) | 0.007 | −2.50 (−3.62 to −1.38) | < 0.001 |
Mean wall area % | 70.11 ± 0.83 | 0.17 (−1.23 to 1.56) | 0.66 (−0.91 to 2.24) | 0.413 | −0.16 (−1.03 to 0.71) | 0.717 |