Variable | Healthy | IPF | p-value |
|---|
Sex | 9 Women, 4 Men | 4 Women, 5 Men | Â |
Age (y) | 61 (13) | 71 (10) | 0.107 |
Height (in) | 66 (3) | 65 (4) | 0.950 |
Weight (lb) | 150 (33) | 168 (39) | 0.549 |
GAP indexa | 1.3 (1.0) | 3.6 (1.4) | 0.003 |
FVC (% predicted)b | 105 (14) | 85 (16) | 0.003 |
DLCO (% predicted)b | 83 (12) | 48 (16) | < 0.001 |
FEV1 (% predicted)b | 102 (13) | 90 (21) | 0.231 |
FEV1/FVCc | 0.75 (0.05) | 0.81 (0.05) | 0.010 |
TLC (% predicted)b | 109 (18) | 72 (17) | < 0.001 |
- Mean (standard deviation) values of demographic variables and pulmonary function test results for the healthy (N = 13) and IPF (N = 9) groups. We used the t-test to evaluate the statistical significance of differences in the mean values between the two groups and made the family-wise Bonferroni correction to the p-values. Abbreviations: DLCO diffusing capacity of carbon monoxide, FEV1 forced expiratory volume in one second, FVC forced vital capacity, GAP gender-age-physiology, IPF idiopathic pulmonary fibrosis, TLC total lung capacity
- aSee Methods Section
- bEntries for FVC, DLCO, FEV1, and TLC are expressed as a percentage of the normal reference value (% predicted)
- cFEV1/FVC denotes the ratio of the raw volumetric measurements (in liters) of FEV1 and FVC
