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Table 1 Baseline patient characteristics

From: Association of time-to-treatment with outcomes of Pneumocystis pneumonia with respiratory failure in HIV-negative patients

Characteristics No. of patients (%) or median (IQR)
Age, years 52.0 (40.5–66.0)
Sex, male 35 (68.6)
Underlying disease
 Malignancy 28 (54.9)
  Hematologic 21
  Solid 7
 Solid organ transplant 18 (35.3)
  Kidney 11
  Liver 4
  Heart 2
  Lung 1
 Othera 5 (9.8)
Immunosuppressive agents used, previous monthb
 Steroid only 18 (35.3)
 Chemotherapy only 29 (56.9)
 Steroid with chemotherapy 4 (7.8)
Prednisolone-equivalent dose, mg, if steroid used 16.1 (6.2–34.7)
Pneumocystis prophylaxis 2 (3.9)
Chest radiography findings
 Pleural effusion 11 (21.6)
 Radiographic pulmonary pattern
  Focal or diffuse alveolar pattern 24 (47.1)
  Focal or diffuse interstitial pattern 5 (9.8)
  Focal or diffuse alveolar-interstitial pattern 22 (43.1)
Laboratory findings on ICU admission
 WBC blood cells,/μL 7960.0 (5320.0–12,225.0)
  Neutrophils,/μL 5458.0 (3245.0–10,395.0)
  Lymphocytes,/μL 580.0 (324.0–1020.0)
 Albumin, g/dL 2.8 (2.4–3.3)
 CRP, mg/dL 12.4 (8.2–19.6)
 PaO2/FiO2 ratio, mmHg 137.2 (112.8–164.6)
 D(A-a)O2, mmHg 39.9 (30.8–52.3)
Organ failure
 Shock 12 (23.5)
 Renal failure requiring renal replacement therapy 1 (2.0)
Respiratory support on ICU admission day
 Mechanical ventilation 43 (84.3)
 High-flow nasal cannula 8 (15.7)
Severity of illness
 SAPS 3 48.0 (37.0–57.5)
 SOFA 6.0 (5.0–8.0)
  1. No. number, IQR interquartile range, ICU intensive care unit, WBC white blood cell, CRP C-reactive protein, PaO2/FiO2 arterial partial pressure of oxygen/fraction of inspired oxygen, D(A-a)O2 alveolar-arterial oxygen gradient, SAPS 3 Simplified Acute Physiology Score 3, SOFA Sequential Organ Failure Assessment
  2. aOthers include 2 glomerulonephritis, 2 interstitial lung disease, and 1 liver cirrhosis
  3. bChemotherapy includes 4 patients with T-cell immunosuppressant