Fig. 6

Co-culture of NHBE with neutrophils from severe asthmatics induces a change in epithelial cell morphology. Quantification of epithelial cell shapes following co-culture with non-asthmatic (left panels) or severe asthmatic (right panels) peripheral blood neutrophils. All measurements were performed using Image J’s shape analysis tools from 3 representative live cell culture images per independent experiment. N = 4, Mean ± SE; P < 0.05(*), P < 0.01(**), P < 0.001(***), P < 0.0001(****)