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Table 2 Cross-sectional characteristics of lobectomised PCD patients (on first post-lung resection assessment) compared to matched controls

From: Prevalence and course of disease after lung resection in primary ciliary dyskinesia: a cohort & nested case-control study

 

Lobectomised PCD (n = 130)

Controls PCD (n = 197)

p-value†

FVC Z score

− 2.41 (− 2.91, − 1.90)

− 1.35 (− 1.70, − 1.00)

0.0001‡

FEV1 Z score

−2.79 (− 3.25, − 2.32)

−1.99 (− 2.32, − 1.65)

0.003‡

BMI Z score

0.03 (− 0.34, 0.40)

− 0.09 (− 0.38, 0.19)

0.599‡

Sputum Culture

 Any Pathogen

60/73 (82.2%)

74/92 (80.4%)

0.774

 Pseudomonas

20/73 (27.4%)

15/92 (16.3%)

0.083

Bronchiectasis

44/46 (95.7%)

86/113 (76.1%)

0.004

Congenital Heart Disease

10/86 (11.6%)

13/126 (10.3%)

0.763

NRDS

37/78 (47.4%)

51/114 (44.7%)

0.712

Chronic Cough

92/95 (96.8%)

99/112 (88.4%)

0.023

Sputum

78/82 (95.1%)

73/81 (90.1%)

0.222

Wheezing

25/63 (39.7%)

58/98 (59.2%)

0.016

Pneumonia

11/66 (16.7%)

35/120 (29.2%)

0.059

Hemoptysis

2/58 (3.5%)

0/67 (0%)

0.125

Rhinorrhea

68/79 (86.1%)

111/123 (90.2%)

0.363

  1. Denominators indicate number of subjects with available data on the specific parameter NRDS: Neonatal Respiratory Distress Syndrome †Pearson Chi Square Test, with the exception of FVC, FEV1 and BMI ‡Paired Samples T test