Skip to main content

Table 1 Features of lobectomised and non-lobectomised patients in the iPCD cohort

From: Prevalence and course of disease after lung resection in primary ciliary dyskinesia: a cohort & nested case-control study

Variable Lobectomised PCD (n = 130) Median (IQR) iPCD Cohort (n = 2733)a Median (IQR) p-value
Age at Presentation (n = 118) 11.5 (6.5, 20.5) 8.8 (4.0, 15.8) < 0.001†
Current Age (n = 130) 24.9 (18.1, 40.1) 18.6 (12.1, 28.3) < 0.001†
% Female 72/130 (55.4%) 1302/2661 (48.9%) 0.150‡
Situs Inversus 27/108 (25.0%) 787/1783 (44.1%) < 0.001‡
Age at lung resection (n = 121) 11.9 (7.7, 16.0)   
Lung resection prior to presentation 52/114 (45.6%)   
Lung resection in childhood 101/121 (83.5%)   
Frequency of lung resection performance per decade (n = 121) < 1969 4   < 0.001‡
1970–1979 11
1980–1989 9
1990–1999 24
2000–2009 34
2010–2017 39
Extent of lung resection (n = 95) One Lobe: 74/95   
(77.9%)
Two lobes: 17/95
(17.9%)
Three Lobes: 2/95
(2.1%)
Four Lobes: 2/95
(2.1%)
Site of lung resectionb (n = 95) RML: 59/121 (48.8%)   
LLL: 33/121 (27.3%)
RLL: 13/121 (10.7%)
Lingula: 9/121 (7.4%)
RUL: 5/121 (4.1%)
LUL: 2/121 (1.7%)
  1. Denominators indicate number of subjects with available data on the specific parameter
  2. RUL: Right Upper Lobe, RML: Right Middle Lobe, RLL: Right Lower Lobe, LUL: Left Upper Lobe, LLL: Left Lower Lobe
  3. aFull iPCD cohort that participated in the study, excluding lobectomised patients (May 2017)
  4. bDenominator reflects the total number of resected lobes. Some patients had more than one lobe resected. For one patient (one with one lobe resected) the exact site was not reported
  5. †Wilcoxon Sum Rank Test
  6. ‡Pearson Chi Square Test