Fig. 5From: Determination of reliable lung function parameters in intubated miceEvaluation of lung function measurement assessed by the NPFE maneuver in mice using orotracheal intubation and tracheostomy, both using the intubation cannula. a, b, Average expiratory flow-volume curves of intubated (“OTI”, in blue) and tracheostomized (“TRA”, in red) mice. n = 16 BALB/cJ mice, n = 16 C57BL/6 J mice. Lower and upper error bars represent standard deviations for intubation and tracheostomy, respectively. c-f, Forced vital capacity (“FVC”, c and e), forced expired volume over 0.1 s (“FEV0.1”, d and f) in intubated and tracheostomized BALB/cJ mice (c, e) and C57BL/6 J mice (d, f). Data represent individual mice and are analyzed by the Wilcoxon signed-rank test or paired t tests. g, i, Relationships between FVC measured in intubated and tracheostomized BALB/cJ (g) and C57BL/6 J (i) mice. h, j, Relationships between FEV0.1 measured in intubated and tracheostomized BALB/cJ (h) and C57BL/6 J (j) mice. k-n, Bland-Altman plots to compare two measurements techniques for FVC in BALB/cJ (k) and C57BL/6 J (m), FEV0.1 in BALB/cJ (l) and C57BL/6 J (n). The upper and lower limits of agreement (95% confidence interval) are shown by a gray dotted lineBack to article page