Skip to main content
Fig. 3 | Respiratory Research

Fig. 3

From: Interferon-γ enhances the antifibrotic effects of pirfenidone by attenuating IPF lung fibroblast activation and differentiation

Fig. 3

INF-γ and PFD inhibit the migration of NHLFs and IPF fibroblasts. Cell migration was assessed using a modified Boyden chamber in NHLFs and IPF fibroblasts treated with either INF-γ [10–40 ng/ml], PFD [300–500 μg/ml] or a combination of IFN-γ/PFD in the upper chamber and PDGF-BB 20 ng/ml used as a chemoattractant in the lower chamber for 24 h. Data are presented as the means ± SEMs of 3 independent experiments each run in duplicate. **P < 0.05 vs. control PDGF-BB and ## P < 0.05 vs. PDGF-BB + vehicle [DMSO]

Back to article page