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Fig. 1 | Respiratory Research

Fig. 1

From: Reduced expression of the Ion channel CFTR contributes to airspace enlargement as a consequence of aging and in response to cigarette smoke in mice

Fig. 1

Development of emphysema-like changes in elderly mice. Healthy 14–20 month old wild-type (WT), CFTR-heterozygous (Het), and CFTR-knockout (KO) mice were sacrificed and lungs were fixed and inflated with formalin. (a) Representative micrographs of lung parenchyma stained with hematoxylin and eosin; and (b) mean linear intercepts (LM) of WT, Het, and KO mice. Magnification: 400X. Scale bar = 50 μm. ***p < .001 via one-way ANOVA with Tukey’s post-hoc multiple comparison. N = 7–9 mice per group

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