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Fig. 1 | Respiratory Research

Fig. 1

From: Compartmentalization of anti-oxidant and anti-inflammatory gene expression in current and former smokers with COPD

Fig. 1

Association of tobacco use with Nrf2 target gene transcription. In the bronchial epithelium there was no difference in Nrf2 expression by smoking status (P = 0.01), but there was higher transcriptional expression of the downstream Nrf2 gene expression in NQO1 (p < 0.001), HO1 (p < 0.001), HO1 (p < 0.001), AKR1C1 (p < 0.001), and AKR1C3 (p < 0.001), which were statistically significant even with the Bonferroni adjusted alpha level of 0.0023 (0.05/22) to account for multiple comparisons

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Respiratory Research

ISSN: 1465-993X

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