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Table 3 Comparison of OR, sensitivity, specificity, PPV, NPV, concordance, and κ coefficient with 95% CI between Cryo and TBB according to PD-L1 expression

From: Comparison of tumor cell numbers and 22C3 PD-L1 expression between cryobiopsy and transbronchial biopsy with endobronchial ultrasonography-guide sheath for lung cancer

 

PD-L1 ≥ 50% (95% CI)

PD-L1 ≥ 1% (95% CI)

OR

45 (1.394–1452)

2 (0.244–16.37)

Sensitivity

66.7% (0.094–0.992)

44.4% (0.137–0.788)

Specificity

100% (0.753–1)

71.4% (0.290–0.963)

PPV

100% (0.158–1)

66.7% (0.223–0.957)

NPV

92.9% (0.661–0.998)

50% (0.187–0.813)

Concordance

93.8% (0.698–0.998)

56.3% (0.299–0.803)

κ coefficient

0.7647 (0.288–1)

0.1515 (0–0.608)

  1. OR odds ratio, PPV positive predict value, NPV negative predict value, CI confidence interval, Cryo cryobiopsy, TBB transbronchial biopsy, PD-L1 programmed death ligand 1
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Respiratory Research

ISSN: 1465-993X

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