From: Are there specific clinical characteristics associated with physician’s treatment choices in COPD?
Characteristics | Treatment category | p-value | ||||
---|---|---|---|---|---|---|
A | B | C | D | E | ||
N = 214 | N = 223 | N = 217 | N = 132 | N = 385 | ||
Age, in year | 64.1 ± 8.4 | 65.6 ± 8.7 | 65.5 ± 8.1 | 65.6 ± 9.1 | 65.4 ± 8.2 | 0,444 |
Gender, male, n(%) | 139 (65.0) | 142 (63.7) | 168 (77.4) | 101 (76.5) | 261 (67.8) | 0.004* |
BMI, kg/m2 | 26.0 ± 5.5 | 26.7 ± 5.8 | 26.1 ± 6.2 | 27.1 ± 6.1 | 25.5 ± 5.8 | 0,051 |
COPD GOLD stages, n(%) | ||||||
GOLD I | 106 (49.5) | 66 (29.6) | 21 (9.7) | 26 (19.7) | 22 (5.7) | < 0.001* |
GOLD II | 82 (38.3) | 124 (55.6) | 106 (48.8) | 58 (43.9) | 131 (34.0) | < 0.001* |
GOLD III | 18 (8.4) | 26 (11.7) | 69 (31.8) | 34 (25.8) | 147 (38.2) | < 0.001* |
GOLD IV | 8 (3.7) | 7 (3.1) | 21 (9.7) | 14 (10.6) | 85 (22.1) | < 0.001* |
FEV1, % predicted | 77.0 ± 20.0 | 69.4 ± 17.5 | 55.8 ± 18.9 | 58.9 ± 21.5 | 47.4 ± 18.7 | < 0.001* |
FVC, % predicted | 99.3 ± 21.1 | 93.5 ± 20.7 | 86.3 ± 22.5 | 85.1 ± 24.2 | 79.6 ± 22.9 | < 0.001* |
Active smoker, n(%) | 111 (52.4) | 93 (41.7) | 73 (33.8) | 54 (41.2) | 118 (31.4) | < 0.001* |
Cumulative smoking, pack-years | 45.2 ± 22.3 | 43.7 ± 19.8 | 47.7 ± 23.9 | 45.4 ± 24.0 | 46.0 ± 23.6 | 0,558 |
MRC Score | 1.2 ± 1.0 | 1.4 ± 0.9 | 1.8 ± 1.0 | 1.7 ± 1.2 | 2.1 ± 1.1 | < 0.001* |
MRC Score ≥ 2, n (%) | 77 (36.0) | 87 (39.0) | 128 (59.0) | 68 (51.5) | 267 (69.4) | < 0.001* |
HAD Score | 11.4 ± 7.3 | 11.2 ± 6.6 | 11.7 ± 6.9 | 12.7 ± 6.9 | 13.6 ± 7.3 | < 0.001* |
CAT score | 14.0 ± 7.2 | 14.8 ± 6.6 | 17.0 ± 7.3 | 17.8 ± 8.5 | 19.1 ± 7.6 | < 0.001* |
DIRECT score | 8.4 ± 6.8 | 9.0 ± 5.7 | 12.2 ± 7.2 | 12.3 ± 8.0 | 14.9 ± 7.7 | < 0.001* |
LTOT, n(%) | 19 (8.9) | 6 (2.7) | 30 (13.8) | 14 (10.6) | 101 (26.2) | < 0.001* |
Long-term NIV, n(%) | 14 (6.5) | 20 (9.0) | 14 (6.5) | 8 (6.1) | 27 (7.0) | 0,801 |
Long-term CPAP, n(%) | 9 (4.2) | 4 (1.8) | 10 (4.6) | 8 (6.1) | 37 (9.6) | < 0.001* |
Exacerbations last year (≥1 severes or ≥ 2 moderate), n (%) | 48 (22.4) | 34 (15.2) | 56 (25.8) | 59 (44.7) | 192 (49.9) | < 0.001* |
Cardio-vascular comorbidity | 117 (54.7) | 142 (63.7) | 123 (56.7) | 80 (60.6) | 228 (59.2) | 0,367 |