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Table 3 Multivariate analysis comparing characteristics of cases and controls with variables stratified by terciles

From: Predictive value of a series of inflammatory markers in COPD for lung cancer diagnosis: a case-control study

Variable

Cases, n (%)

Controls, n (%)

OR (95%CI) a

p

OR (95%CI) b

p

A1AT (mg/dl)

 Low: < 138

27 (24.7)

41 (49.4)

1 (−)

 

1 (−)

 

 Medium: ≥138 and < 167

32 (29.3)

32 (38.5)

1.49 (0.66–3.39)

0.34

0.96 (0.38–2.45)

0.94

 High: ≥167

50 (45.9)

10 (12)

7.33 (2.80–19.24)

< 0.001

3.60 (1.23–10.53)

0.019

Cholesterol (mg/dl)

 Low: < 168

40 (36.7)

18 (21.7)

2.91 (1.43–5.94)

0.003

2.91 (1.08–7.85)

0.03

 Medium: ≥168 and < 200

44 (40.4)

25 (30.1)

3.73 (1.74–8.00)

0.001

3.03 (1.09–8.41)

0.03

 High: ≥200

25 (22.9)

40 (48.2)

1 (−)

 

1 (−)

 

Neutrophils (per μl)

 Low: < 4007

22 (20.2)

45 (54.2)

1(−)

 

1 (−)

 

 Medium: ≥4007 and < 5955

42 (38.5)

25 (30.1)

3.35 (1.65–6.84)

0.001

2.95 (1.14–7.60)

0.02

 High: ≥5955

45 (41.3)

13 (15.7)

7.08 (3.18–15.77)

< 0.001

4.90 (1.60–14.94)

0.005

  1. OR: odds-ratio; 95%CI: confidence interval of a 95%; A1AT: alpha 1-antitripsin; a OR adjusted by age and gender; b OR adjusted by age, gender, alpha 1-antitripsin, cholesterol and neutrophils