Table 2 The top 30 genes differentially expressed by prednisone at 5% FDR in study 1
Gene | GeneName | FC | P-value | FDR | Direction |
|---|---|---|---|---|---|
KLRF1 | killer cell lectin-like receptor subfamily F, member 1 | 1.73 | 1.16E-06 | 2.48.E-03 | down |
GZMH | granzyme H | 1.64 | 1.84E-05 | 1.42.E-02 | down |
ADGRG1 | adhesion G protein-coupled receptor G1 | 1.58 | 8.37E-07 | 2.14.E-03 | down |
KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 1.54 | 5.04E-06 | 6.46.E-03 | down |
GZMA | granzyme A | 1.48 | 2.68E-05 | 1.90.E-02 | down |
DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 1.48 | 1.31E-06 | 2.52.E-03 | down |
PDGFD | platelet derived growth factor D | 1.46 | 1.22E-05 | 1.13.E-02 | down |
GZMB | granzyme B | 1.46 | 3.08E-07 | 1.27.E-03 | down |
NKG7 | natural killer cell granule protein 7 | 1.42 | 1.88E-06 | 3.29.E-03 | down |
S1PR5 | sphingosine-1-phosphate receptor 5 | 1.40 | 3.30E-07 | 1.27.E-03 | down |
C1orf21 | chromosome 1 open reading frame 21 | 1.40 | 5.70E-05 | 2.74.E-02 | down |
GNLY | granulysin | 1.38 | 4.84E-05 | 2.59.E-02 | down |
WLS | wntless Wnt ligand secretion mediator | 1.36 | 6.34E-05 | 2.91.E-02 | down |
SYTL2 | synaptotagmin-like 2 | 1.36 | 4.29E-05 | 2.43.E-02 | down |
PRF1 | perforin 1 (pore forming protein) | 1.35 | 3.83E-05 | 2.23.E-02 | down |
SLAMF7 | SLAM family member 7 | 1.33 | 2.53E-06 | 4.06.E-03 | down |
SPON2 | spondin 2, extracellular matrix protein | 1.33 | 1.96E-07 | 1.27.E-03 | down |
TGFBR3 | transforming growth factor beta receptor III | 1.28 | 1.05E-04 | 4.11.E-02 | down |
NCR1 | natural cytotoxicity triggering receptor 1 | 1.28 | 1.00E-04 | 4.09.E-02 | down |
PIGB | phosphatidylinositol glycan anchor biosynthesis class B | 1.28 | 8.89E-07 | 2.14.E-03 | down |
FAM174A | family with sequence similarity 174, member A | 1.27 | 3.55E-05 | 2.20.E-02 | down |
CEP78 | centrosomal protein 78 kDa | 1.27 | 6.84E-05 | 3.06.E-02 | down |
ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 1.27 | 2.27E-07 | 1.27.E-03 | down |
ABCB1 | ATP binding cassette subfamily B member 1 | 1.26 | 1.23E-05 | 1.13.E-02 | down |
OSBPL5 | oxysterol binding protein-like 5 | 1.24 | 1.02E-04 | 4.09.E-02 | down |
CYSLTR2 | cysteinyl leukotriene receptor 2 | 1.24 | 3.08E-06 | 4.23.E-03 | down |
SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | 1.23 | 5.57E-05 | 2.74.E-02 | down |
MILR1 | mast cell immunoglobulin-like receptor 1 | 1.23 | 1.24E-04 | 4.78.E-02 | up |
USP28 | ubiquitin specific peptidase 28 | 1.23 | 3.83E-05 | 2.23.E-02 | down |
CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 1.22 | 5.92E-05 | 2.78.E-02 | down |