From: Defining a role for lung function associated gene GSTCD in cell homeostasis
Protein Structure Results | I-TASSER | SWISS-MODEL | Phyre2 | |||
---|---|---|---|---|---|---|
Variant 1 | Variant 2 | Variant 1 | Variant 2 | Variant 1 | Variant 2 | |
Predicted Secondary Structure | Primarily α-helices with intermittent coil structures. β-strands only present at termini. | N/A | Primarily intermittent α-helices (45%). β-strands only present at termini (12%). Two predicted transmembrane regions (30-40aa and 281-299aa). | Primarily intermittent α-helices (55%). β-strands only present at termini (10%). Two predicted transmembrane regions (29-38aa and 194-212aa). | ||
Regions of Primary Sequence Homology | Primarily across the MTF domain to C-terminus. Partial matches across whole protein. | Only across the MTF domain to C-terminus | Only across the MTF domain | |||
Intrinsic disorder | N/A | Low disorder across C-terminus | High disorder across C-terminus | Two theoretical central regions of disorder (27%):• 204-270aa• 325-386aa | Two theoretical central regions of disorder (26%):• 118-184aa• 257-299aa | |
Top 3 Structural Templates | Putative MTF Importin β subunit Exodeoxyribonuclease | Ras guanyl-releasing protein 1 MTF | Protein RdmB MTF Protein RdmB MTF Protein RdmB MTF | Putative rRNA methylase Putative rRNA methylase rRNA small subunit MTF | rRNA small subunit MTF Transferase S-adenosyl-L-methionine-dependent MTF | Transferase NADB-Rossmann fold superfamily protein S-adenosyl-L-methionine-dependent MTF |