Circulating ESM-1 levels are correlated with the presence of coronary artery disease in patients with obstructive sleep apnea

Table 2 Association between clinical or biochemical variables and CAD

Variables	OR	95%CI	P value
Age (year)	1.091	1.056–1.126	< 0.001**
Gender (male = 1, female = 2)	1.906	0.765–4.753	0.166
BMI (kg/m²)	0.954	0.884–1.029	0.220
SBP (mmHg)	0.991	0.972–1.014	0.379
DBP (mmHg	0.962	0.934–0.991	0.012*
TC (mmol/l)	0.397	0.278–0.568	< 0.001**
TG (mmol/l)	0.723	0.514–1.016	0.062
HDL-C (mmol/l)	0.900	0.654–1.239	0.520
LDL-C (mmol/l)	0.405	0.273–0.599	< 0.001**
FBG (mmol/l)	1.134	0.942–1.366	0.185
ALT (mmol/l)	1.002	0.988–1.016	0.817
AST (mmol/l)	1.017	0.990–1.045	0.207
AHI (events/h)	0.966	0.951–0.981	< 0.001**
LSaO₂(%)	1.114	1.065–1.116	< 0.001**
ESM-1(per100pg)	1.258	1.150–1.376	< 0.001**

Dependent variable: CAD
BMI Body mass index, SBP Systolic blood pressure, DBP Diastolic blood pressure, TC Total cholesterol, TG Triglyceride, HDL-C High density lipoprotein, LDL-C Low density lipoprotein, FBG Fasting blood glucose, ALT Alanine aminotransferase, AST Aspartate aminotransferase, AHI Apnea-hypopnea index, LSaO₂ Lowest oxygen saturation, ESM-1 Endothelial cell specific molecules-1
* P < 0.05 in ordinal logistic regression analysis,** P < 0.001 in ordinal logistic regression analysis

ISSN: 1465-993X