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Table 1 Demographic details and baseline characteristics of study participants

From: Systemic Immuno-metabolic alterations in chronic obstructive pulmonary disease (COPD)

 

HNS (n = 16)

HS (n = 13)

TS-COPD (n = 14)

p-value

Age (y)

53.38 ± 10.43

60.15 ± 8.754

68.36 ± 8.924

< 0.001

Gender (M/F)

8 M/8F

13 M/0F

14 M/0F

N/A

BMI

24.31 ± 3.909

23.71 ± 2.814

19.75 ± 3.12

< 0.01

Fasting BSL (mg/dL)

88.63 ± 12.1

91.54 ± 16.22

95.31 ± 11.68

NS

Smoking history, Pack years (Ex:Current)

N/A

32.69 ± 17.37 (2:11)

39.45 ± 29.98 (6:8)

NS

FEV1 (% Predicted)

104.3 ± 10.57

97.72 ± 9.394

51.09 ± 26.24

< 0.001

FVC (% Predicted)

102.3 ± 13.3

95.08 ± 11.46

85.85 ± 20.78

< 0.05

FVC/FEV1%

102.5 ± 6.387

103.3 ± 4.426

58.12 ± 19.49

< 0.001

COPD gold stage (I/II/III/IV)

N/A

N/A

3/2/6/3

N/A

Monocytes (%)

5.786 ± 0.699

7.5 ± 1.446

7.556 ± 1.667

< 0.01

(/μL)

435.9 ± 119

595.6 ± 148.9

619.4 ± 224

< 0.05

Neutrophils (%)

55.93 ± 12.39

53.58 ± 8.051

60.44 ± 6.966

NS

(/μL)

4186 ± 1170

4390 ± 1431

5033 ± 1656

NS

Lymphocytes (%)

34.43 ± 10.41

34.83 ± 7.158

29.11 ± 5.667

NS

(/μL)

2612 ± 1124

2810 ± 792.1

2359 ± 705.4

NS

Eosinophils (%)

3.857 ± 2.685

4.083 ± 3.37

2.889 ± 1.833

NS

(/μL)

280.3 ± 194.4

345.8 ± 371.1

266.2 ± 260.8

NS

  1. Data is represented as mean ± standard deviation. HNS Healthy non-smokers, HS Healthy smokers and TS-COPD Tobacco-smoking – COPD subjects. ANOVA statistical analysis was performed and p < 0.05 was considered significant. NS Non-significant and N/A Not applicable