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Table 1 Risk of Bias for all studies included in the systematic review

From: Monoclonal antibodies in type 2 asthma: a systematic review and network meta-analysis

Study (Ref) Random Sequence Generation Allocation Concealment Selective Reporting Other Bias Blinding Incomplete outcome data BIAS judgement
Flood-Page et al. 2007 [50] Unclear Unclear Low High Unclear Low High Risk
Busse et al. 2008 [68] Unclear Unclear Low Unclear Low Low High Risk
Haldar et al. 2009 [49] Low Unclear Low Unclear Unclear Low Intermediate Risk
Corren et al. 2011 [18] Low Low Low Unclear Low Low Low Risk
Castro et al. 2011 [54] Unclear Unclear Low Unclear Low Low Intermediate Risk
Pavord et al. 2012 [15] Low Low Low Unclear Low Low Low Risk
Noonan et al. 2013 [57] Unclear Unclear Low Unclear Unclear Low High Risk
Wenzel et al. 2013 [65] Low Low Low Unclear Low Low Low Risk
Oh et al. 2013 [20] Low Low Unclear Unclear Low Unclear Low Risk
Piper et al. 2013 [59] Low Unclear Low Unclear Unclear Low Intermediate Risk
De Boever et al. 2014 [62] Low Low Low Unclear Low Low Low Risk
Ortega et al. 2014 [36] Low Unclear Low Unclear Low Unclear Intermediate Risk
Castro et al. 2014 [42] Low Low Low Unclear Low Low Low Risk
Hanania et al. 2015 [33] Low Low Unclear Unclear Low Low Intermediate Risk
Brightling et al. 2015 [61] Low Low Low Unclear Unclear Low Intermediate Risk
Castro et al. 2015 [37] Low Low Low Unclear Low Low Low Risk
Hanania et al. 2016 [34] Low Low Low Unclear Low Low Low Risk
Bjermer et al. 2016 [53] Unclear Unclear Unclear Unclear Unclear Unclear High Risk
Corren et al. 2016 [52] Unclear Unclear Low Unclear Unclear Low High Risk
Bleecker et al. 2016 [38] Low Unclear Low Unclear Low Low Intermediate Risk
FitzGerald et al. 2016 [39] Low Low Low Unclear Low Low Low Risk
Park et al. 2016 [40] Low Unclear Low Low Low Low Low Risk
Nowak et al. 2016 [41] Low Unclear Low Unclear Low Low Intermediate Risk
Wenzel et al. 2016 [64] Low Low Low Unclear Low Low Low Risk
Corren et al. 2017 [13] Low Low Low Unclear Low Low Low Risk
Chupp et al. 2017 [48] Low Low Low Unclear Low Low Low Risk
Ferguson et al. 2017 [46] Low Low Low Unclear Low High Intermediate Risk
Panettieri et al. 2018 [35] Low Low Low Unclear Low Low Low Risk
Russel et al. 2018 [60] Low Low Low Unclear Low Low Low Risk
Castro et al. 2018 [19] Low Unclear Low High Low Low High Risk
  1. Risk of bias assessed by Cochrane tool for randomized controlled trials. Thirty studies were assessed for their risk of bias. Underlined studies are included in the meta-analysis