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Table 1 Characteristics of patients who underwent pulmonary surgery or non-pulmonary surgery

From: Postoperative acute exacerbation of interstitial pneumonia in pulmonary and non-pulmonary surgery: a retrospective study

Characteristics

Pulmonary surgeries

Non-pulmonary surgeries

P value

  

% or (IQR)

[n]

 

% or (IQR)

[n]

 

N, no

151

34.0%

 

291

66.0%

  

Acute exacerbation, no

5

3.3%

[151]

4

1.4%

[291]

P = 0.284

Age, median

69

(65.0–78.0)

[151]

71

(63.0–75.0)

[291]

p = 0.027†

Sex Male, no

115

76.2%

[151]

173

59.5%

[291]

p = 0.001†

BMI (kg/m2), median

22.1

(19.7–24.9)

[151]

22.6

(19.8–24.8)

[291]

p = 0.503

History of smoking, no

114

78.6%

[145]

158

64.8%

[244]

p = 0.004†

IPF or other IP, no

59

39.1%

[151]

89

30.6%

[291]

p = 0.089

Corticosteroids therapy, no

26

17.3%

[151]

86

29.6%

[291]

p = 0.006†

Past acute exacerbation, no

2

1.3%

[151]

7

2.4%

[291]

p = 0.725

HRCT findings

 UIP pattern, no

74

49.0%

[151]

130

44.7%

[291]

p = 0.421

 Emphysema, no

77

51.0%

[151]

106

36.7%

[291]

p = 0.004†

Pulmonary function test

 %VC, median (%)

98.5

(85.1–112.8)

[140]

96.5

(79.9–107.9)

[236]

p = 0.089

 FEV1/FVC, median (%)

76.7

(68.2–82.6)

[140]

77.8

(71.5–83.7)

[236]

p = 0.049†

 %DLCO, median (%)

65.2

(53.5–81.5)

[127]

51.3

(41.7–70.1)

[49]

p = 0.001†

KL-6, median (U/mL)

487

(311–825.5)

[145]

547

(337–923.5)

[145]

p = 0.307

LDH, median (U/L)

193

(170–224)

[150]

206

(179–254.5)

[284]

p = 0.008†

CRP, median (mg/dL)

0.21

(0.1–0.6)

[151]

0.25

(0.1–1.2)

[287]

p = 0.169

JACS risk score, median

10

(6.8–11)

[138]

7

(4–8)

[133]

p < 0.001†

Emergency surgery, no

0

0%

[151]

12

4.1%

[291]

p = 0.010†

Tumor surgery, no

96

63.6%

[151]

122

41.9%

[291]

p < 0.001†

Neoadjuvant chemotherapy, no

1

1.1%

[94]

12

9.8%

[122]

p = 0.008†

Anesthesia time, median (min)

273

(191–336)

[141]

271

(187–388)

[277]

p = 0.409

Amount of bleeding, median (mL)

70

(15.0–180.5)

[141]

110

(23.0–450.0)

[275]

p = 0.002†

Lung infection

10

6.6%

[151]

8

2.8%

[291]

p = 0.073

 (surgical complication), no

       
  1. IQR interquartile range, BMI body mass index, IPF idiopathic pulmonary fibrosis, IP interstitial pneumonia, HRCT high resolution computed tomography, UIP usual interstitial pneumonia, VC vital capacity, FEV1/FVC forced expiratory volume in 1 second/forced vital capacity, DLCO diffusing capacity for carbon monoxide, KL-6 Klebs von den Lungen-6, LDH lactate dehydrogenase, CRP C-reactive protein, JACS Japanese association for chest surgery
  2. †; P value < 0.05, Fisher’s exact test or Wilcoxon test