Table 4 Demography, baseline (pre-bronchodilator) and maximal (post-bronchodilator) PFTs, in four imaging-based clusters
Cluster 1 | Cluster 2 | Cluster 3 | Cluster 4 | P value | |
|---|---|---|---|---|---|
N = 100 | N = 80 | N = 141 | N = 85 | ||
Demography | |||||
GOLD (%) (0/1/2/3/4) | 62/23/14/1/0 | 57/20/20/2/0 | 6/24/51/16/3 | 2/0/12/46/40 | < 0.0001 |
Strata (%) (2/3/4) | 62/37/1 | 57/40/2 | 6/74/19 | 2/12/86 | < 0.0001 |
BODE index | 0.28 (0.61) | 0.60 (1.12) | 1.31 (1.78) | 3.99 (2.00) | < 0.0001 |
Sex (Female %) | 32 | 64 | 34 | 41 | 0.00015 |
Race (White/African-American/Other) | 88/6/6 | 75/20/5 | 91/4/5 | 84/12/5 | 0.0088 |
Age (yrs.) | 64.91 (7.11) | 66.59 (7.92) | 69.37 (5.94) | 65.67 (7.92) | < 0.0001 |
BMI (kg/m2) | 28.67 (4.43) | 30.76 (4.55) | 28.49 (4.6) | 25.68 (4.44) | < 0.0001 |
PFT Baseline lung function a | |||||
FEV1% predicted | 88 (18) | 79 (16) | 59 (20) | 31 (15) | < 0.0001 |
FVC % predicted | 97 (14) | 88 (14) | 85 (18) | 71 (19) | < 0.0001 |
FEV1/FVC × 100 | 68 (10) | 68 (9) | 51 (11) | 32 (10) | < 0.0001 |
PFT Maximal lung function b | |||||
FEV1% predicted | 95 (17) | 86 (16) | 68 (19) | 37 (17) | < 0.0001 |
FVC % predicted | 101 (14) | 91 (14) | 94 (17) | 80 (20) | < 0.0001 |
FEV1/FVC × 100 | 72 (10) | 71 (9) | 53 (11) | 34 (12) | < 0.0001 |