Table 2 Major imaging-based features selected by Wilk’s λ value of a stepwise forward variable selection method in four imaging-based clusters and healthy subjects (stratum 1)
Variable | Region | Wilk’s λ value | Cluster 1 (N = 100) | Cluster 2 (N = 80) | Cluster 3 (N = 141) | Cluster 4 (N = 85) | P value | Stratum 1 (N = 69) |
|---|---|---|---|---|---|---|---|---|
βtissueRV | Total | 0.286 | 0.240 (0.041) | 0.245 (0.041) | 0.172 (0.026) | 0.110 (0.020) | < 0.0001 | 0.264 (0.054) |
Jacobian | Total | 0.145 | 2.16 (0.259) | 1.67 (0.200) | 1.63 (0.201) | 1.32 (0.147) | < 0.0001 | 2.11 (0.378) |
Emph% | Total | 0.116 | 5.8 (0.058) | 2.4 (0.026) | 10.4 (0.073) | 25.0 (0.110) | < 0.0001 | 0.024 (0.028) |
fSAD% | Total | 0.093 | 8.7 (0.065) | 7.5 (0.055) | 23.5 (0.086) | 36.8 (0.074) | < 0.0001 | 0.050 (0.052) |
βtissueTLC | Total | 0.080 | 0.109 (0.015) | 0.142 (0.019) | 0.103 (0.014) | 0.081 (0.014) | < 0.0001 | 0.122 (0.03) |