Table 1 Demography, baseline (Pre-bronchodilator) and maximal (Post-bronchodilator) pulmonary function tests for 105 Stratum 1 (healthy), 119 Stratum 2, 184 Stratum 3 and 103 Stratum 4 subjects
Stratum 1 (Healthy) | Stratum 2 | Stratum 3 | Stratum 4 | P value | |
|---|---|---|---|---|---|
N = 69 | N = 119 | N = 184 | N = 103 | ||
Demography | |||||
Age, yrs | 58.6 (10.5) | 65.1 (7.5) | 69.1 (6.4) | 65.2 (7.5) | < 0.0001 |
BMI, kg/m2 | 28.4 (5.2) | 29.5 (4.8) | 28.4 (4.6) | 27.0 (4.7) | < 0.0001 |
Sex, (Male/Female %) | 42/58 | 51.3/48.7 | 62.5/37.5 | 57.3/42.7 | = 0.02 |
Race, Caucasian/ African American/ Other (%) | 62.3/26.1/ 11.6 | 81.5/12.6/ 5.9 | 88.0 /7.1/ 4.9 | 85.4 /9.7/ 4.9 | < 0.0001 |
Baseline lung function a | |||||
FEV1% predicted | 98 (13) | 91 (14) | 67 (16) | 28 (8) | < 0.0001 |
FVC % predicted | 98 (11) | 94 (13) | 91 (16) | 67 (15) | < 0.0001 |
FEV1/FVC × 100 | 78 (6) | 74 (6) | 55 (9) | 32 (9) | < 0.0001 |
Maximal lung function b | |||||
FEV1% predicted | 102 (12) | 97 (14) | 76 (15) | 34 (10) | < 0.0001 |
FVC % predicted | 98 (11) | 95 (13) | 99 (15) | 76 (17) | < 0.0001 |
FEV1/FVC × 100 | 81 (6) | 78 (5) | 57 (8) | 34 (9) | < 0.0001 |