Table 1 Baseline clinical characteristics in participants with idiopathic pulmonary fibrosis. Data are shown for all subjects with IPF and then for the population separated in to those with progressive or stable disease at 12 months. Data are mean (SD) or n (%), unless otherwise stated. BMI = body-mass index. FVC = forced vital capacity. DLCO = diffusion capacity for carbon monoxide. CPI = composite physiological index, *Number of subjects analysed due to missing data
Variable | All (n = 145) | Progressive (n = 73) | Stable (n = 71) |
|---|---|---|---|
Age (years) | 71.7 (7.7) | 71.8 (8.3) | 71.5 (7.1) |
Sex (male) | 117 (80.7%) | 58 (79.5%) | 59 (83.1%) |
Ethnicity | |||
Caucasian | 142 (97.9%) | 71 (97.3%) | 70 (98.6%) |
Asian | 2 (1.4%) | 1 (1.4%) | 1 (1.4%) |
Mixed race | 1 (0.7%) | 1 (1.4%) | |
Ever Smokers | 108 (74.5%) | 54 (74.0%) | 54 (76.1%) |
BMI (kg/m2) | 28.4 (4.4) *n = 144 | 28.7 (4.7) *n = 72 | 28.0 (4.1) *n = 71 |
FVC (% predicted) | 79.8 (20.4) *n = 140 | 75.6 (20.4) *n = 69 | 83.8 (19.9) *n = 70 |
DLCO ((% predicted) | 48.2 (17.9) *n = 129 | 41.1 (11.9) *n = 61 | 54.7 (20.1) *n = 67 |
12 month-baseline FVC (% predicted) | −4.6 (11.7) *n = 95 | −16.4 (10.1) *n = 32 | 1.5 (6.9) *n = 63 |
12 month-baseline TLCO (% predicted) | −3.8 (7.7) *n = 75 | −10.2 (6.3) *n = 22 | −1.1 (6.6) *n = 53 |
CPI | 44.9 (14.9) *n = 129 | 50.5 (11.1) *n = 61 | 39.8 (16.3) *n = 67 |
Median follow-up days | 1051 (584, 1180) | 609 (196, 1092) | 1128.0 (1050, 1212) |