Table 1 Clinical variables of the subjects enrolled in the analysis of the cellular immune response
From: Multi-level immune response network in mild-moderate Chronic Obstructive Pulmonary Disease (COPD)
Non-Smokers | Smokers | COPD-FS | COPD-CS | P value | |
|---|---|---|---|---|---|
n = 12 | n = 9 | n = 16 | n = 28 | ||
Age (years) | 67.6 ± 9.5 | 58.0 ± 9.3 | 64.5 ± 8.1 | 67.8 ± 7.8 | 0.0587 |
Gender (M/F) | 3/9 | 5/4 | 14/2 | 20/8 | 0.0051 |
Pack/year | – | 36.8 ± 19.1 | 48.7 ± 19.9 | 51.1 ± 22.1 | 0.1830 |
BMI (Kg/m2) | 28.0 ± 6.7 | 27.4 ± 5.4 | 24.9 ± 3.8 | 28.0 ± 3.5 | 0.0974 |
FEV1/FVC (%) | 77.9 ± 4.1 | 79.1 ± 10.1 | 61.7 ± 6.5 | 59.9 ± 7.1 | 0.0000 |
FEV1 (% ref) | 97.3 ± 8.1 | 95.1 ± 7.5 | 77.1 ± 13.0 | 77.3 ± 18.3 | 0.0001 |
DLCO (% ref.) | 78.3 ± 16.2 | 78.9 ± 11.4 | 61.6 ± 9.6 | 71.4 ± 14.7 | 0.0021 |
WBC 10^9/L | 7.5 ± 2.1 | 9.3 ± 4.01 | 6.5 ± 2.2 | 8.6 ± 2. 2 | 0.0193 |
Abs Neutrophil count (10^9/L) | 5.0 ± 2.1 | 6.1 ± 4.0 | 4.0 ± 1.6 | 5.5 ± 1.8 | 0.0448 |
hsCRP mg/dl | 0.72 ± 0.96 | 8.56 ± 18.09 | 0.62 ± 0.98 | 2.43 ± 4.94 | 0.0954 |