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Fig. 7 | Respiratory Research

Fig. 7

From: Tenofovir alafenamide fumarate attenuates bleomycin-induced pulmonary fibrosis by upregulating the NS5ATP9 and TGF-β1/Smad3 signaling pathway

Fig. 7

Illustration of the anti-fibrotic effects and their relationship between TAF and NS5ATP9 in BLM-induced pulmonary fibrosis. By originally up-regulating the expression level of NS5ATP9, TAF suppresses BLM-induced lung fibrosis via inhibition of differentiation of fibroblast into myofibroblast and ECM production, as well as down-regulating the expression level of collagen 3α1, fibronectin, and αSMA, in addition to TGF-β1/Smad3 signaling pathway

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Respiratory Research

ISSN: 1465-993X

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