Fig. 1

Rev-D4F suppresses LPS-induced lung injury in endotoxemic mice. Mice were treated with LPS and/or Rev-D4F for 48 h, sacrificed, and the left lung lobes were used to determine the wet: dry ratio a The plasma was used to detect the levels of ET-1 b and TNF-α c The right lobes of the lungs were stained with Hematoxylin-eosin (× 200); the scale bar represents 50 μm d The alveolar wall thickness was quantified e The numbers of red f and white blood cells g were analyzed. Data are presented as mean ± SD (n = 6; **P < 0.01)