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Table 3 The skin viscoelastic modulus is an independent predictor of pulmonary emphysema and airflow obstruction

From: Loss of skin elasticity is associated with pulmonary emphysema, biomarkers of inflammation, and matrix metalloproteinase activity in smokers

 

Bivariate

Multiple Regressiona

 

β

P-value

β

P-value

%LAA

 VE

−0.23

0.0004

−0.26

0.003

 FWS

0.11

0.09

0.14

0.11

Perc15

 VE

0.17

0.009

0.24

0.001

 FWS

− 0.04

0.58

−0.06

0.39

FEV1 (%pred)

 VE

0.09

0.164

0.18

0.013

 FWS

−0.02

0.73

−0.07

0.35

FEV1/FVC (%pred)

 VE

0.24

0.0003

0.26

0.001

 FWS

−0.11

0.08

−0.13

0.07

DLCO (%pred)

 VE

0.38

<0.0001

0.35

<0.0001

 FWS

−0.13

0.04

−0.13

0.038

RV/TLC

 VE

−0.28

<0.0001

−0.16

0.03

 FWS

0.01

0.09

0.06

0.35

  1. Notes. DLCO, diffusion capacity for carbon monoxide; FEV1, forced expiratory volume in 1 s; FWS, facial wrinkling score; FVC, forced vital capacity in 1 s; LAA% = low attenuation areas, tissue voxels with Hounsfield Unit attenuation values less than −950; Perc15, cut off value in Hounsfield units below which 15% of all voxels are distributed; RV, residual volume; TLC, total lung capacity; VE; skin viscoelastic modulus
  2. aAdjusted for age, gender, sun exposure, active smoking and pack year smoking history
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Respiratory Research

ISSN: 1465-993X

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